BD-PT6068

FIG4 Rabbit Polyclonal Antibody

Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)

常规抗体

FIG4 KIAA0274 SAC3

FIG4

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

9896

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9896

Q92562

http://www.uniprot.org/uniprotkb/Q92562/entry

103199

Q91WF7

http://www.uniprot.org/uniprot/Q91WF7

Synthesized peptide derived from human FIG4. at AA range: 341-390

This antibody detects endogenous levels of FIG4

WB 1:500-2000, ELISA 1:10000-20000

110kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008],

Endosome membrane . Localization requires VAC14 and PIKFYVE. .

phospholipid metabolic process,?glycerophospholipid metabolic process,?vacuole organization,?behavior,?locomotory behavior,?cell death,?death,?organophosphate metabolic process,?neuron differentiation,?phosphoinositide metabolic process,?pigmentation,?glycerolipid metabolic process,?neuron development,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.