产品名称
NUT Rabbit Polyclonal Antibody
别名
Protein NUT (Nuclear protein in testis)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=256646
Human Swissprot No.
Q86Y26
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86Y26/entry
Mouse Swissprot No.
Q8BHP2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BHP2
免疫原
Synthesized peptide derived from human NUT. at AA range: 1082-1131
特异性
This antibody detects endogenous levels of NUT
稀释度
WB 1:500-2000, ELISA 1:10000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with BRD4 which produces a BRD4-NUT fusion protein.,disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with BRD3 which produces a BRD3-NUT fusion protein.,PTM:Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export.,similarity:Belongs to the FAM22 family.,subcellular location:Shuttles between nucleus and cytoplasm.,tissue specificity:Specifically expressed in testis.,
组织表达
Specifically expressed in testis.
细胞定位
Cytoplasm . Nucleus . Shuttles between nucleus and cytoplasm. .
功能
disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with BRD4 which produces a BRD4-NUT fusion protein.,disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with BRD3 which produces a BRD3-NUT fusion protein.,PTM:Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export.,similarity:Belongs to the FAM22 family.,subcellular location:Shuttles between nucleus and cytoplasm.,tissue specificity:Specifically expressed in testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
