产品名称
RPA14 Rabbit Polyclonal Antibody
别名
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)
蛋白名称
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6119
Human Swissprot No.
P35244
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P35244/entry
Mouse Swissprot No.
Q9CQ71
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CQ71
免疫原
Synthetic peptide from human protein at AA range: 30-80
特异性
The antibody detects endogenous RPA14
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RPA4.,
信号通路
DNA replication;Nucleotide excision repair;Mismatch repair;Homologous recombination;
功能
function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RPA4.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
