产品名称
BLBP Rabbit Polyclonal Antibody
别名
Fatty acid-binding protein, brain (Brain lipid-binding protein) (BLBP) (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7) (Mammary-derived growth inhibitor related)
基因名称
FABP7 BLBP FABPB MRG
蛋白名称
Fatty acid-binding protein, brain (Brain lipid-binding protein) (BLBP) (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7) (Mammary-derived growth inhibitor related)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2173
Human Swissprot No.
O15540
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O15540/entry
Mouse Swissprot No.
P51880
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P51880
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P55051
免疫原
Synthetic peptide from human protein at AA range: 80-132
特异性
The antibody detects endogenous BLBP
稀释度
WB 1:500-2000, ELISA 1:10000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016],
组织表达
Expressed in brain and other neural tissues.
功能
domain:Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.,function:B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,tissue specificity:Expressed in brain and other neural tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.