BD-PT5895

IL-19 Rabbit Polyclonal Antibody

Interleukin-19 (IL-19;Melanoma differentiation-associated protein-like protein;NG.1)

常规抗体

IL19 ZMDA1

Interleukin-19 (IL-19) (Melanoma differentiation-associated protein-like protein) (NG.1)

WB

Human,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

29949

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29949

Q9UHD0

http://www.uniprot.org/uniprotkb/Q9UHD0/entry

329244

Q8CJ70

http://www.uniprot.org/uniprot/Q8CJ70

Synthetic peptide from human protein at AA range: 51-100

The antibody detects endogenous IL-19

WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000. IF 1:50-200

20kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],

Secreted.

Cytokine-cytokine receptor interaction;Jak_STAT;

function:May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis.,similarity:Belongs to the IL-10 family.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.