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Cystatin A Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT5876
产品名称
Cystatin A Rabbit Polyclonal Antibody
别名
Cystatin-A (Cystatin-AS;Stefin-A)
类别
常规抗体
基因名称
CSTA STF1 STFA
蛋白名称
Cystatin-A (Cystatin-AS) (Stefin-A)
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
1475
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1475
Human Swissprot No.
P01040
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P01040/entry
Mouse Gene ID
209294
Mouse Swissprot No.
P56567
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P56567
免疫原
Synthetic peptide from human protein at AA range: 60-98
特异性
The antibody detects endogenous Cystatin A
稀释度
WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000. IF 1:50-200
预测分子量
11kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008],
组织表达
Expressed in the skin throughout the epidermis.
细胞定位
Cytoplasm .
功能
function:This is an intracellular thiol proteinase inhibitor.,similarity:Belongs to the cystatin family.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of 293T mouse-kidney lysate, antibody was diluted at 1000. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200

Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200

Immunohistochemical analysis of paraffin-embedded human-thymus, antibody was diluted at 1:200

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