产品名称
TMOD2 Rabbit Polyclonal Antibody
别名
Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.13% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/29767
Human Swissprot No.
Q9NZR1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NZR1/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/50876
Mouse Swissprot No.
Q9JKK7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JKK7
Rat Gene Link
https://www.uniprot.org/uniprot/58814
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P70566
免疫原
Synthesized peptide derived from human TMOD2 AA range: 138-188
特异性
This antibody detects endogenous levels of TMOD2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008],
组织表达
Neuronal-tissue specific.
细胞定位
Cytoplasm, cytoskeleton .
功能
function:Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.,similarity:Belongs to the tropomodulin family.,subunit:Binds to the N-terminus of tropomyosin and to actin.,tissue specificity:Neuronal-tissue specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.