产品名称
F105B Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.17% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/90268
Human Swissprot No.
Q96BN8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96BN8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/432940
Mouse Swissprot No.
Q3UCV8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UCV8
免疫原
Synthesized peptide derived from human F105B AA range: 284-334
特异性
This antibody detects endogenous levels of F105B at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016],
功能
similarity:Belongs to the FAM105 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
