产品名称
CACTIN Rabbit Polyclonal Antibody
蛋白名称
chromosome 19 open reading frame 29
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58509
Human Swissprot No.
Q8WUQ7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8WUQ7/entry
Mouse Swissprot No.
Q9CS00
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CS00
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CACTIN. AA range:141-190
特异性
The antibody detects endogenous CACTIN protein
稀释度
WB 1:500-2000, ELISA 1:10000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
caution:An ORF (C19orf029 OS) has been described in the opposite strand of the C-terminus of this gene.,function:May be involved in pre-mRNA splicing.,miscellaneous:Antigen recognized by autologous antibody in patients with renal-cell carcinoma.,subunit:Identified in the spliceosome C complex, at least composed of AQR, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRNP200, SNRNP40, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, XAB2 and ZCCHC8.,
组织表达
Cervix,Epithelium,Renal cell carcinoma,Uterus,
细胞定位
Nucleus . Cytoplasm, cytosol . Nuclear localization with a speckled expression pattern in some cells. Colocalizes with NFKBIL1 in the nucleus. .
功能
caution:An ORF (C19orf029 OS) has been described in the opposite strand of the C-terminus of this gene.,function:May be involved in pre-mRNA splicing.,miscellaneous:Antigen recognized by autologous antibody in patients with renal-cell carcinoma.,subunit:Identified in the spliceosome C complex, at least composed of AQR, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRNP200, SNRNP40, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, XAB2 and ZCCHC8.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
