产品名称
CSH1 Rabbit Polyclonal Antibody
蛋白名称
chorionic somatomammotropin hormone 1 (placental lactogen)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1442
Human Swissprot No.
P01243
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P01243/entry
免疫原
Synthetic peptide from human protein at AA range: 161-210
特异性
The antibody detects endogenous CSH1 protein
稀释度
IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, al
细胞定位
extracellular region,endoplasmic reticulum,vesicle,membrane-bounded vesicle,
信号通路
Neuroactive ligand-receptor interaction;Jak_STAT;
功能
function:Similar to that of somatotropin.,miscellaneous:The sequence of CSH1 is shown.,similarity:Belongs to the somatotropin/prolactin family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
