产品名称
NOP56 Rabbit Polyclonal Antibody
别名
Nucleolar protein 56 (Nucleolar protein 5A)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10528
Human Swissprot No.
O00567
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O00567/entry
Mouse Swissprot No.
Q9D6Z1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D6Z1
免疫原
Synthesized peptide derived from NOP56 at AA range: 191-240
特异性
NOP56 Polyclonal Antibody detects endogenous levels of NOP56
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016],
组织表达
Brain,Cervix carcinoma,Epithelium,Uterus,
细胞定位
Nucleus, nucleolus . Cytoplasm . Nucleus, nucleoplasm .
功能
function:Required for 60S ribosomal subunit biogenesis.,similarity:Belongs to the NOP5/NOP56 family.,similarity:Contains 1 Nop domain.,subunit:Interacts with NOP1 and NOP58.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
