产品名称
PCDA9 Rabbit Polyclonal Antibody
别名
Protocadherin alpha-9 (PCDH-alpha-9)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.214% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9752
Human Swissprot No.
Q9Y5H5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y5H5/entry
免疫原
Synthesized peptide derived from human PCDA9 AA range: 395-445
特异性
This antibody detects endogenous levels of PCDA9 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
function:Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.,similarity:Contains 6 cadherin domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
