BD-PT5759

PI 3 Kinase Class 3 Rabbit Polyclonal Antibody

phosphoinositide-3-kinase, class 3

常规抗体

PIK3C3 VPS34

PI 3 Kinase Class 3

WB

Human,Mouse,Rat,Predicted:Cow:PIG

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

5289

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5289

Q8NEB9

http://www.uniprot.org/uniprotkb/Q8NEB9/entry

225326

Q6PF93

http://www.uniprot.org/uniprot/Q6PF93

O88763

http://www.uniprot.org/uniprot/O54941O88763

Synthetic Peptide of PI 3 Kinase Class 3

This antibody detects endogenous levels of PI 3 Kinase Class 3 Polyclonal Antibody at Human;Mouse;Rat;Predicted:Cow:PIG

WB 1:500-2000;IHC-p 1:50-300

100kD

-20°C/1 year

Polyclonal, Rabbit,IgG

catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.,cofactor:Manganese.,function:Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity). Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4.,tissue specificity:Ubiquitously expressed, with a highest expression in skeletal muscle.,

Ubiquitously expressed, with a highest expression in skeletal muscle.

Midbody . Late endosome . Cytoplasmic vesicle, autophagosome . As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes (PubMed:14617358). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity). .

Inositol phosphate metabolism;Phosphatidylinositol signaling system;Regulation of autophagy;

catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.,cofactor:Manganese.,function:Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity). Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4.,tissue specificity:Ubiquitously expressed, with a highest expression in skeletal muscle.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.