产品名称
DND1 Rabbit Polyclonal Antibody
别名
Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.33% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/373863
Human Swissprot No.
Q8IYX4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IYX4/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/213236
Mouse Swissprot No.
Q6VY05
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6VY05
免疫原
Synthesized peptide derived from human DND1 AA range: 94-144
特异性
This antibody detects endogenous levels of DND1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17. [provided by RefSeq, Dec 2010],
细胞定位
Nucleus . Cytoplasm . Perinuclear germ granules, also called germ plasm or chromatoid body. Colocalizes in perinuclear sites with APOBEC3 (By similarity). .
功能
function:May play a role during primordial germ cell (PGC) development. However, does not seem to be essential for PGC migration.,similarity:Contains 2 RRM (RNA recognition motif) domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
