产品名称
Calretinin Rabbit Polyclonal Antibody
别名
Calretinin (CR;29 kDa calbindin)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=794
Human Swissprot No.
P22676
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P22676/entry
Mouse Swissprot No.
Q08331
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q08331
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P47728
免疫原
Synthesized peptide derived from calbindin 2 at AA range: 191-240
特异性
Calretinin Polyclonal Antibody detects endogenous levels of calbindin 2
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],
细胞定位
nucleus,cytoplasm,cytosol,gap junction,neuron projection,terminal bouton,synapse,
功能
function:Calretinin is a calcium-binding protein which is abundant in auditory neurons.,online information:Calbindin entry,similarity:Belongs to the calbindin family.,similarity:Contains 6 EF-hand domains.,tissue specificity:Brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
