产品名称
TP53INP2 Rabbit Polyclonal Antibody
别名
TP53INP2; C20orf110; DOR; PINH; Tumor protein p53-inducible nuclear protein 2; Diabetes and obesity-regulated gene; p53-inducible protein U; PIG-U
蛋白名称
Tumor protein p53-inducible nuclear protein 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58476
Human Swissprot No.
Q8IXH6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8IXH6/entry
Mouse Swissprot No.
Q8CFU8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8CFU8
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human TP53INP2. AA range:161-210
特异性
TP53INP2 Polyclonal Antibody detects endogenous levels of TP53INP2 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
tumor protein p53 inducible nuclear protein 2(TP53INP2) Homo sapiens The protein encoded by this gene promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1/RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes. [provided by RefSeq, Jul 2016],
细胞定位
Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
