产品名称
IL-1F10 Rabbit Polyclonal Antibody
别名
IL1F10; FIL1T; IL1HY2; FKSG75; Interleukin-1 family member 10; IL-1F10; FIL1 theta; Interleukin-1 HY2; IL-1HY2; Interleukin-1 theta; IL-1 theta
蛋白名称
Interleukin-1 family member 10
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84639
Human Swissprot No.
Q8WWZ1
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8WWZ1/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=215274
Mouse Swissprot No.
Q8R459
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R459
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat Swissprot Link
http://www.uniprot.org/uniprot/
免疫原
Synthesized peptide derived from Interleukin-1 family member 10 at AA range: 101-150
特异性
IL-1F10 Polyclonal Antibody detects endogenous levels of IL-1F10 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008],
组织表达
Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.
细胞定位
Cytoplasm . Secreted . The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .
功能
function:Binds soluble IL-1 receptor type 1.,online information:Interleukin-1 entry,similarity:Belongs to the IL-1 family.,tissue specificity:Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.