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IL-1F10 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT5725
产品名称
IL-1F10 Rabbit Polyclonal Antibody
别名
IL1F10; FIL1T; IL1HY2; FKSG75; Interleukin-1 family member 10; IL-1F10; FIL1 theta; Interleukin-1 HY2; IL-1HY2; Interleukin-1 theta; IL-1 theta
类别
常规抗体
基因名称
IL1F10
蛋白名称
Interleukin-1 family member 10
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
84639
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84639
Human Swissprot No.
Q8WWZ1
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8WWZ1/entry
Mouse Gene ID
215274
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=215274
Mouse Swissprot No.
Q8R459
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R459
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat Swissprot Link
http://www.uniprot.org/uniprot/
免疫原
Synthesized peptide derived from Interleukin-1 family member 10 at AA range: 101-150
特异性
IL-1F10 Polyclonal Antibody detects endogenous levels of IL-1F10 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
预测分子量
17kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008],
组织表达
Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.
细胞定位
Cytoplasm . Secreted . The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .
功能
function:Binds soluble IL-1 receptor type 1.,online information:Interleukin-1 entry,similarity:Belongs to the IL-1 family.,tissue specificity:Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of MOUSE-KIDNEY MOUSE-HEART MOUSE-BRAIN MOUSE-SPLEEN RAT-SPLEEN using IL1F10 antibody. Antibody was diluted at 1:2000. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:200

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