产品名称
CTACK Rabbit Polyclonal Antibody
别名
CCL27; ILC; SCYA27; C-C motif chemokine 27; CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; Skinkine; Small-inducible cytokine A27
蛋白名称
C-C motif chemokine 27
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10850
Human Swissprot No.
Q9Y4X3
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y4X3/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100039863
Mouse Swissprot No.
Q9Z1X0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9Z1X0
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat Swissprot Link
http://www.uniprot.org/uniprot/
免疫原
Synthesized peptide derived from C-C motif chemokine 27 at AA range: 51-100
特异性
CTACK Polyclonal Antibody detects endogenous levels of CTACK protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014],
组织表达
Testis, thymus, placenta, ovary and skin.
信号通路
Cytokine-cytokine receptor interaction;Chemokine;Intestinal immune network for IgA production;
功能
function:Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.,online information:CCL27 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,tissue specificity:Testis, thymus, placenta, ovary and skin.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
