产品名称
PLEK2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.38% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/26499
Human Swissprot No.
Q9NYT0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NYT0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/27260
Mouse Swissprot No.
Q9WV52
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WV52
免疫原
Synthesized peptide derived from human PLEK2 AA range: 5-55
特异性
This antibody detects endogenous levels of PLEK2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015],
细胞定位
Cell projection, lamellipodium membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
功能
function:May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation.,similarity:Contains 1 DEP domain.,similarity:Contains 2 PH domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
