产品名称
IL-26 Rabbit Polyclonal Antibody
别名
IL26; AK155; Interleukin-26; IL-26; Protein AK155
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55801
Human Swissprot No.
Q9NPH9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NPH9/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat Swissprot Link
http://www.uniprot.org/uniprot/
免疫原
Synthesized peptide derived from Interleukin-26 at AA range: 21-70
特异性
IL-26 Polyclonal Antibody detects endogenous levels of IL-26 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq, Jul 2008],
组织表达
Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level).
信号通路
Cytokine-cytokine receptor interaction;Jak_STAT;
功能
induction:By Herpesvirus saimiri infection.,online information:Interleukin-26 entry,similarity:Belongs to the IL-10 family.,subunit:Homodimer.,tissue specificity:Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.