产品名称
CD56 Rabbit Polyclonal Antibody
别名
NCAM1; NCAM; Neural cell adhesion molecule 1; N-CAM-1; NCAM-1; CD56
蛋白名称
Neural cell adhesion molecule 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4684
Human Swissprot No.
P13591
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P13591/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Mouse Swissprot No.
P13595
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P13595
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat Swissprot Link
http://www.uniprot.org/uniprot/
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human NCAM1. AA range:250-300
特异性
CD56 Polyclonal Antibody detects endogenous levels of CD56 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],
组织表达
Brain,Brain cortex,Kidney,Ovary,Plasma,Skeletal muscle,Testis,
细胞定位
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 4]: Cell membrane ; Lipid-anchor, GPI-anchor .; [Isoform 5]: Secreted.; [Isoform 6]: Secreted .
信号通路
Cell adhesion molecules (CAMs);Prion diseases;
功能
function:This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.,online information:N-CAM 140,online information:NCAM entry,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
