产品名称
ATOH1 Rabbit Polyclonal Antibody
别名
Protein atonal homolog 1 (Class A basic helix-loop-helix protein 14) (bHLHa14) (Helix-loop-helix protein hATH-1) (hATH1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.46% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/474
Human Swissprot No.
Q92858
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92858/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/11921
Mouse Swissprot No.
P48985
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P48985
免疫原
Synthesized peptide derived from human ATOH1 AA range: 38-88
特异性
This antibody detects endogenous levels of ATOH1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. [provided by RefSeq, Jul 2008],
功能
function:Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. May play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
