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GDF-7 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT5654
产品名称
GDF-7 Rabbit Polyclonal Antibody
别名
GDF7; Growth/differentiation factor 7; GDF-7
类别
常规抗体
基因名称
GDF7
蛋白名称
Growth/differentiation factor 7
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
151449
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=151449
Human Swissprot No.
Q7Z4P5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q7Z4P5/entry
Mouse Gene ID
238057
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=238057
Mouse Swissprot No.
P43029
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P43029
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat Swissprot Link
http://www.uniprot.org/uniprot/
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human GDF7. AA range:321-370
特异性
GDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
预测分子量
47kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016],
组织表达
Testis,
细胞定位
Secreted .
信号通路
TGF-beta;
功能
function:May play an active role in the motor area of the primate neocortex.,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western Blot analysis of Hela cells using GDF-7 Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200

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