产品名称
GDF-3 Rabbit Polyclonal Antibody
别名
GDF3; Growth/differentiation factor 3; GDF-3
蛋白名称
Growth/differentiation factor 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9573
Human Swissprot No.
Q9NR23
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NR23/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14562
Mouse Swissprot No.
Q07104
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q07104
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat Swissprot Link
http://www.uniprot.org/uniprot/
免疫原
Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360
特异性
GDF-3 Polyclonal Antibody detects endogenous levels of GDF-3 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],
细胞定位
Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. .
功能
online information:GDF3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.