产品名称
OTX1 Rabbit Polyclonal Antibody
别名
Homeobox protein OTX1 (Orthodenticle homolog 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.61% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5013
Human Swissprot No.
P32242
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P32242/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/18423
Mouse Swissprot No.
P80205
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P80205
Rat Gene Link
https://www.uniprot.org/uniprot/25646
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q63410
免疫原
Synthesized peptide derived from human OTX1 AA range: 236-286
特异性
This antibody detects endogenous levels of OTX1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
组织表达
Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level).
功能
developmental stage:Embryo.,function:Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.,similarity:Belongs to the paired homeobox family. Bicoid subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Expressed in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
