产品名称
CD240d Rabbit Polyclonal Antibody
别名
RHD; Blood group Rh(D) polypeptide; RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen; CD240D
蛋白名称
Blood group Rh(D) polypeptide
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6007
Human Swissprot No.
Q02161
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q02161/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19746
Mouse Swissprot No.
Q8CF94
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8CF94
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60414
Rat Swissprot Link
http://www.uniprot.org/uniprot/O88298
免疫原
Synthesized peptide derived from Blood group Rh(D) polypeptide at AA range: 161-210
特异性
CD240d Polyclonal Antibody detects endogenous levels of CD240d protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Restricted to tissues or cell lines expressing erythroid characters.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.,online information:Blood group antigen gene mutation database,polymorphism:RHD and RHCE are responsible for the Rh blood group system. The molecular basis of the Tar=Rh40 blood group antigen is a polymorphism in position 110.,similarity:Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.,tissue specificity:Restricted to tissues or cell lines expressing erythroid characters.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
.jpg)
