产品名称
T3HPD Rabbit Polyclonal Antibody
别名
Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-l-proline dehydratase)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.62% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/112849
Human Swissprot No.
Q96EM0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96EM0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67217
Mouse Swissprot No.
Q9CXA2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CXA2
免疫原
Synthesized peptide derived from human T3HPD AA range: 11-61
特异性
This antibody detects endogenous levels of T3HPD at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a dehydratase that converts trans-3-hydroxy-L-proline to delta(1)-pyrroline-2-carboxylate. This enzyme may function to degrade dietary proteins that contain trans-3-hydroxy-L-proline as well as other proteins such as collagen IV. The encoded protein can be converted to an epimerase by changing a threonine to a cysteine at a catalytic site. [provided by RefSeq, Sep 2016],
组织表达
Ubiquitously expressed.
功能
catalytic activity:L-proline = D-proline.,function:Catalyzes the interconversion of L- and D-proline.,miscellaneous:In contrast to the T.cruzi enzyme, lacks the conserved Cys at position 273 which is replaced by a Thr residue. The high conservation of the protein nevertheless suggests that it is nevertheless active.,similarity:Belongs to the proline racemase family.,subunit:Homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
