产品名称
ATX3L Rabbit Polyclonal Antibody
别名
Putative ataxin-3-like protein (EC 3.4.19.12) (Machado-Joseph disease protein 1-like)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.64% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/92552
Human Swissprot No.
Q9H3M9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H3M9/entry
免疫原
Synthesized peptide derived from human ATX3L AA range: 99-149
特异性
This antibody detects endogenous levels of ATX3L at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This intronless gene may be a pseudogene (PMID:11450850). This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease. [provided by RefSeq, Sep 2011],
功能
caution:Could be the product of a pseudogene. Suggested by the absence of intron.,function:May bind to histones and regulate transcription. May act as a deubiquitinating enzyme.,similarity:Contains 1 Josephin domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.