BD-PT5610

CD138 Rabbit Polyclonal Antibody

SDC1; SDC; Syndecan-1; SYND1; CD138

常规抗体

SDC1

Syndecan-1

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

6382

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6382

P18827

http://www.uniprot.org/uniprotkb/P18827/entry

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=

P18828

http://www.uniprot.org/uniprot/P18828

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=

http://www.uniprot.org/uniprot/

The antiserum was produced against synthesized peptide derived from the Internal region of human SDC1. AA range:191-240

CD138 Polyclonal Antibody detects endogenous levels of CD138 protein.

WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

34kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008],

Dermoid cancer,Fibroblast,Kidney,Mammary gland,Placenta,

Membrane ; Single-pass type I membrane protein . Secreted . Secreted, extracellular exosome . Shedding of the ectodomain produces a soluble form. .

ECM-receptor interaction;Cell adhesion molecules (CAMs);

function:Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Interacts with CDCP1.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.