产品名称
KLF2 Rabbit Polyclonal Antibody
别名
Krueppel-like factor 2 (Lung krueppel-like factor)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.70% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10365
Human Swissprot No.
Q9Y5W3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y5W3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/16598
Mouse Swissprot No.
Q60843
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q60843
Rat Gene Link
https://www.uniprot.org/uniprot/306330
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9ET58
免疫原
Synthesized peptide derived from human KLF2 AA range: 196-246
特异性
This antibody detects endogenous levels of KLF2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011],
组织表达
Brain,Hair follicle dermal papilla,Lung,Spleen,
功能
function:Binds to the CACCC box in the beta-globin gene promoter and activates transcription.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with WWP1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.