产品名称
SPSB3 Rabbit Polyclonal Antibody
别名
SPRY domain-containing SOCS box protein 3 (SSB-3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.73% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/90864
Human Swissprot No.
Q6PJ21
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PJ21/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/79043
Mouse Swissprot No.
Q571F5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q571F5
免疫原
Synthesized peptide derived from human SPSB3 AA range: 102-152
特异性
This antibody detects endogenous levels of SPSB3 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Brain,Eye,Hypothalamus,Testis,
功能
domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,sequence caution:Intron retention.,similarity:Belongs to the SPSB family.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 SOCS box domain.,subunit:Interacts with MET.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
