产品名称
Dkk-1 Rabbit Polyclonal Antibody
别名
DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK
蛋白名称
Dickkopf-related protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22943
Human Swissprot No.
O94907
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O94907/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13380
Mouse Swissprot No.
O54908
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O54908
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat Swissprot Link
http://www.uniprot.org/uniprot/
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human DKK1. AA range:181-230
特异性
Dkk-1 Polyclonal Antibody detects endogenous levels of Dkk-1 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],
功能
function:Inhibitor of Wnt signaling pathway.,similarity:Belongs to the dickkopf family.,tissue specificity:Placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
