产品名称
Neurotensin Rabbit Polyclonal Antibody
别名
NTS; Neurotensin/neuromedin N
蛋白名称
Neurotensin/neuromedin N
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4922
Human Swissprot No.
P30990
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P30990/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67405
Mouse Swissprot No.
Q9D3P9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D3P9
Rat Swissprot Link
http://www.uniprot.org/uniprot/P20068
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human NTS. AA range:121-170
特异性
Neurotensin Polyclonal Antibody detects endogenous levels of Neurotensin protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014],
细胞定位
Secreted. Cytoplasmic vesicle, secretory vesicle. Packaged within secretory vesicles.
功能
function:Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.,online information:Neurotensin entry,similarity:Belongs to the neurotensin family.,subcellular location:Packaged within secretory vesicles.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
