产品名称
DMRT2 Rabbit Polyclonal Antibody
别名
Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.85% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10655
Human Swissprot No.
Q9Y5R5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y5R5/entry
免疫原
Synthesized peptide derived from human DMRT2 AA range: 315-365
特异性
This antibody detects endogenous levels of DMRT2 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010],
组织表达
Expressed in testis, kidney and skeletal muscle.
功能
similarity:Belongs to the DMRT family.,similarity:Contains 1 DM DNA-binding domain.,tissue specificity:Expressed in testis, kidney and skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
