产品名称
EST4A Rabbit Polyclonal Antibody
别名
Carboxylesterase 4A (EC 3.1.1.-)
基因名称
CES4A CES8 UNQ440/PRO873
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.87% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/283848
Human Swissprot No.
Q5XG92
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q5XG92/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/0
Mouse Swissprot No.
Q8R0W5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R0W5
免疫原
Synthesized peptide derived from human EST4A AA range: 441-491
特异性
This antibody detects endogenous levels of EST4A at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme, and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined. [provided by RefSeq, Jun 2010],
功能
function:Probable carboxylesterase.,similarity:Belongs to the type-B carboxylesterase/lipase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
