产品名称
CD200 Rabbit Polyclonal Antibody
别名
CD200; MOX1; MOX2; My033; OX-2 membrane glycoprotein; CD200
蛋白名称
OX-2 membrane glycoprotein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4345
Human Swissprot No.
P41217
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P41217/entry
Mouse Swissprot No.
O54901
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O54901
Rat Swissprot Link
http://www.uniprot.org/uniprot/P04218
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD200. AA range:171-220
特异性
CD200 Polyclonal Antibody detects endogenous levels of CD200 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
组织表达
Blood,Brain,Fetal brain,
细胞定位
Cell membrane; Single-pass type I membrane protein.
功能
function:Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD200R1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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