BD-PT5470

IL-1RII Rabbit Polyclonal Antibody

IL1R2; IL1RB; Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD121b

常规抗体

IL1R2

Interleukin-1 receptor type 2

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

7850

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7850

P27930

http://www.uniprot.org/uniprotkb/P27930/entry

P27931

http://www.uniprot.org/uniprot/P27931

The antiserum was produced against synthesized peptide derived from the Internal region of human IL1R2. AA range:141-190

IL-1RII Polyclonal Antibody detects endogenous levels of IL-1RII protein.

WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

43kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012],

B-cell,Colon,Ovary,

[Isoform Short]: Secreted .; [Isoform Long]: Cell membrane; Single-pass type I membrane protein.

MAPK_ERK_Growth;MAPK_G_Protein;Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;

function:Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1ra).,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.