BD-PT5409-Inhibin β-A Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

Inhibin β-A Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT5409

产品名称

Inhibin β-A Rabbit Polyclonal Antibody

别名

INHBA; Inhibin beta A chain; Activin beta-A chain; Erythroid differentiation protein; EDF

类别

常规抗体

基因名称

INHBA

蛋白名称

Inhibin beta A chain

推荐应用

反应种属

Human,Mouse,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

3624

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3624

Human Swissprot No.

P08476

Human Swissprot Link

http://www.uniprot.org/uniprotkb/P08476/entry

Mouse Gene ID

16323

Mouse Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16323

Mouse Swissprot No.

Q04998

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q04998

Rat Gene ID

29200

Rat Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29200

Rat Swissprot No.

P18331

Rat Swissprot Link

http://www.uniprot.org/uniprot/P18331

免疫原

The antiserum was produced against synthesized peptide derived from the C-terminal region of human INHBA. AA range:377-426

特异性

Inhibin β-A Polyclonal Antibody detects endogenous levels of Inhibin β-A protein.

稀释度

WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

预测分子量

52kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. [provided by RefSeq, Aug 2016],

组织表达

Dermoid cancer,Eye,Fetal brain,Testis,

细胞定位

Secreted.

信号通路

Cytokine-cytokine receptor interaction;TGF-beta;

功能

function:Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.,online information:Activin entry,similarity:Belongs to the TGF-beta family.,subunit:Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysate from 293, MCF-7 cells, using INHBA Antibody.

Western Blot analysis of MCF-7, 293 cells using Inhibin β-A Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded Human liver. 1, Antibody was diluted at 1:200（4°,overnight）. 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200（room temperature, 30min）.