产品名称
Inhibin β-B Rabbit Polyclonal Antibody
别名
INHBB; Inhibin beta B chain; Activin beta-B chain
蛋白名称
Inhibin beta B chain
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3625
Human Swissprot No.
P09529
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P09529/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16324
Mouse Swissprot No.
Q04999
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q04999
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25196
Rat Swissprot Link
http://www.uniprot.org/uniprot/P17491
免疫原
Synthesized peptide derived from Inhibin beta B chain at AA range: 351-400
特异性
Inhibin β-B Polyclonal Antibody detects endogenous levels of Inhibin β-B protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Polymorphisms near this gene are associated with pre-eclampsia in female human patients. [provided by RefSeq, Aug 2016],
信号通路
Cytokine-cytokine receptor interaction;TGF-beta;
功能
function:Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.,online information:Inhibin entry,similarity:Belongs to the TGF-beta family.,subunit:Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.