产品名称
CTBL1 Rabbit Polyclonal Antibody
别名
Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19)
基因名称
CTNNBL1 C20orf33 PP8304
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.107% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/56259
Human Swissprot No.
Q8WYA6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WYA6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/66642
Mouse Swissprot No.
Q9CWL8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CWL8
Rat Gene Link
https://www.uniprot.org/uniprot/296320
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4V8K2
免疫原
Synthesized peptide derived from human CTBL1 AA range: 293-343
特异性
This antibody detects endogenous levels of CTBL1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013],
组织表达
Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid.
细胞定位
[Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm .
功能
function:Induces apoptosis in CHO cells.,tissue specificity:Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
