产品名称
MER34 Rabbit Polyclonal Antibody
别名
HERV-MER_4q12 provirus ancestral Env polyprotein (Endogenous retrovirus group MER34 member 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.109% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/100288413
Human Swissprot No.
Q9H9K5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H9K5/entry
免疫原
Synthesized peptide derived from human MER34 AA range: 391-441
特异性
This antibody detects endogenous levels of MER34 at Human
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed at high level in the placenta and stem cells (at protein level) (PubMed:28739914). Also expressed in the kidney but at a lower level (PubMed:28739914). Endogenous retroviral envelope protein HEMO, secreted form: Present in the blood of pregnant women (at protein level) (PubMed:28739914).
细胞定位
[Endogenous retroviral envelope protein HEMO]: Cell membrane ; Single-pass type I membrane protein . This uncleaved form present at the cell surface represents the major form (PubMed:28739914). .; [Endogenous retroviral envelope protein HEMO, secreted form]: Secreted . This secreted form, which is released in the extracellular medium following cleavage, constitutes a minor form (PubMed:28739914). .
功能
function:Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.,similarity:Belongs to the gamma type-C retroviral envelope protein family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
