产品名称
CE112 Rabbit Polyclonal Antibody
别名
Centrosomal protein of 112 kDa (Coiled-coil domain-containing protein 46)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.234% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/201134
Human Swissprot No.
Q8N8E3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8N8E3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/76380
Mouse Swissprot No.
Q5PR68
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5PR68
免疫原
Synthesized peptide derived from human CE112 AA range: 475-525
特异性
This antibody detects endogenous levels of CE112 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],
组织表达
Lung,PCR rescued clones,Testis,Uterus,
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes around spindle poles in some cells. .
功能
sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 563.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
