产品名称
ZKSC1 Rabbit Polyclonal Antibody
别名
Zinc finger protein with KRAB and SCAN domains 1 (Zinc finger protein 139) (Zinc finger protein 36) (Zinc finger protein KOX18)
基因名称
ZKSCAN1 KOX18 ZNF139 ZNF36
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.112% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/7586
Human Swissprot No.
P17029
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P17029/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/74570
Mouse Swissprot No.
Q8BGS3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BGS3
Rat Gene Link
https://www.uniprot.org/uniprot/498160
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4KLI1
免疫原
Synthesized peptide derived from human ZKSC1 AA range: 313-363
特异性
This antibody detects endogenous levels of ZKSC1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010],
组织表达
Brain,Epithelium,Eye,Fetal kidney,Insulinoma,Lung,Lymphoid,Pancreas,Spleen,
功能
function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 6 C2H2-type zinc fingers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
