产品名称
Histone H1 (Mono Methyl Lys25) Mouse Polyclonal Antibody
别名
H1K25ME1; HIST1H1A; H1F1; Histone H1.1; Histone H1a; HIST1H1C; H1F2; Histone H1.2; Histone H1c; Histone H1d; Histone H1s-1; HIST1H1D; H1F3; Histone H1.3; Histone H1c; Histone H1s-2; HIST1H1E; H1F4; Histone H1.4; Histone H1b; Histone H1s-4
基因名称
HIST1H1A/HIST1H1C/HIST1H1D/HIST1H1E
蛋白名称
Histone H1.1/Histone H1.2/Histone H1.3/Histone H1.4
存储缓冲液
PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.
Human Gene ID
3024/3006/3007/3008
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3024
Human Swissprot No.
Q02539/P16403/P16402/P10412
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q02539/entry
Mouse Gene ID
80838/50708/14957/50709
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80838
Rat Gene ID
291145/201097
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=291145
Rat Swissprot No.
D4A3K5/P15865
Rat Swissprot Link
http://www.uniprot.org/uniprot/D4A3K5
免疫原
Synthetic Peptide of Histone H1 (Mono Methyl Lys25)
特异性
The antibody detects endogenous Histone H1 (Mono Methyl Lys25) protein.
背景介绍
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015],
细胞定位
Nucleus . Chromosome . Mainly localizes in euchromatin.
功能
function:Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.,similarity:Belongs to the histone H1/H5 family.,
纯化
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
