产品名称
KLF13 Rabbit Polyclonal Antibody
别名
KLF13; BTEB3; NSLP1; Krueppel-like factor 13; Basic transcription element-binding protein 3; BTE-binding protein 3; Novel Sp1-like zinc finger transcription factor 1;RANTES factor of late activated T-lymphocytes 1; RFLAT-1; Transcription factor BTEB3; Transcription factor NSLP1
蛋白名称
Krueppel-like factor 13
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51621
Human Swissprot No.
Q9Y2Y9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y2Y9/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50794
Mouse Swissprot No.
Q9JJZ6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JJZ6
免疫原
The antiserum was produced against synthesized peptide derived from human KLF13 around the non-acetylation site of Lys166. AA range:131-180
特异性
KLF13 Polyclonal Antibody detects endogenous levels of KLF13 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008],
功能
domain:The Ala/Pro-rich domain may contain discrete activation and repression subdomains and also can mediate protein-protein interactions.,function:Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.,PTM:Phosphorylated.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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