Cn|En

现货抗体产品库

IDH3A Rabbit Polyclonal Antibody

产品详情 相关文献 产品问答 相关产品

产品基本信息

产品货号
BD-PT5318
产品名称
IDH3A Rabbit Polyclonal Antibody
别名
IDH3A; Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha
类别
常规抗体
基因名称
IDH3A
蛋白名称
Isocitrate dehydrogenase [NAD] subunit alpha mitochondrial
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
3419
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3419
Human Swissprot No.
P50213
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P50213/entry
Mouse Gene ID
67834
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67834
Mouse Swissprot No.
Q9D6R2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D6R2
Rat Gene ID
114096
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=114096
Rat Swissprot No.
Q99NA5
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q99NA5
免疫原
Synthesized peptide derived from the Internal region of human IDH3A.
特异性
IDH3A Polyclonal Antibody detects endogenous levels of IDH3A protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
预测分子量
39kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008],
组织表达
Brain,Brain cortex,Cajal-Retzius cell,Esophagus tumor,Fetal
细胞定位
Mitochondrion.
信号通路
Citrate cycle (TCA cycle);
功能
catalytic activity:Isocitrate + NAD(+) = 2-oxoglutarate + CO(2) + NADH.,cofactor:Binds 1 magnesium or manganese ion per subunit.,similarity:Belongs to the isocitrate and isopropylmalate dehydrogenases family.,subunit:Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western Blot analysis of MCF-7, HT29, mouse brain, mouse heart, mouse colon, mouse kidney, mouse skeletal muscle cells using IDH3A Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-心, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded human-lymph-gland, antibody was diluted at 1:100

相关文献

产品问答

相关产品

免责声明| 法律支持| 联系方式

市场:027-65023363   行政/人事:027-62439686   邮箱:marketing@brainvta.com  

销售总监:张经理  18995532642  华东区:陈经理 18013970337   华南区:王经理 13100653525   华中/西区:杨经理 18186518905   华北区:张经理 18893721749

地址:中国武汉东湖高新区光谷七路128号中科开物产业园1号楼

Copyright © 武汉枢密脑科学技术有限公司. All RIGHTS RESERVED.
鄂ICP备2021009124号 DIGITAL BY VTHINK