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GDI-2 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT5317
产品名称
GDI-2 Rabbit Polyclonal Antibody
别名
GDI2; RABGDIB; Rab GDP dissociation inhibitor beta; Rab GDI beta; Guanosine diphosphate dissociation inhibitor 2; GDI-2
类别
常规抗体
基因名称
GDI2
蛋白名称
Rab GDP dissociation inhibitor beta
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
2665
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2665
Human Swissprot No.
P50395
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P50395/entry
Mouse Gene ID
14569
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14569
Mouse Swissprot No.
Q61598
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61598
Rat Gene ID
29662
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29662
Rat Swissprot No.
P50399
Rat Swissprot Link
http://www.uniprot.org/uniprot/P50399
免疫原
Synthesized peptide derived from the C-terminal region of human GDI-2.
特异性
GDI-2 Polyclonal Antibody detects endogenous levels of GDI-2 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
预测分子量
50kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
组织表达
Ubiquitous.
细胞定位
Cytoplasm . Membrane ; Peripheral membrane protein .
功能
function:Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.,similarity:Belongs to the Rab GDI family.,tissue specificity:Ubiquitous.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western Blot analysis of A549, HT29, K562, mouse kidney, mouse lung cells using GDI-2 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100

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