产品名称
HSP 90 Rabbit Polyclonal Antibody
别名
HSP90AA1; HSP90A; HSPC1; HSPCA; Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; HSP86; Renal carcinoma antigen NY-REN-38; HSP90AB1; HSP90B; HSPC2; HSPCB; Heat shock protein HSP 90-beta; HSP 90; Heat shock 84 kDa; HSP 84; HSP84
蛋白名称
Heat shock protein HSP 90-alpha/Heat shock protein HSP 90-beta
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3326
Human Swissprot No.
P07900/P08238
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P07900/entry
Mouse Gene ID
15519/15516
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15519
Mouse Swissprot No.
P07901/P11499
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P07901
Rat Gene ID
299331/301252
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=299331
Rat Swissprot No.
P82995/P34058
Rat Swissprot Link
http://www.uniprot.org/uniprot/P82995
免疫原
The antiserum was produced against synthesized peptide derived from human HSP90A/B around the non-acetylation site of Lys292/284. AA range:251-300
特异性
HSP 90 Polyclonal Antibody detects endogenous levels of HSP 90 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
组织表达
Adult brain,Brain,Brain cortex,Breast,Cajal-Retzius
细胞定位
Nucleus . Cytoplasm . Melanosome . Cell membrane . Mitochondrion . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
信号通路
Antigen processing and presentation;NOD-like receptor;Progesterone-mediated oocyte maturation;Pathways in cancer;Prostate cancer;
功能
caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,function:Molecular chaperone.,function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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