产品名称
SCCA1/2 Rabbit Polyclonal Antibody
别名
SERPINB3; SCCA; SCCA1; Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6317
Human Swissprot No.
P29508
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P29508/entry
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINB3/4. AA range:111-160
特异性
SCCA1/2 Polyclonal Antibody detects endogenous levels of SCCA1/2 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
developmental stage:Its expression is closely related to cellular differentiation in both normal and malignant squamous cells.,function:May act as a protease inhibitor to modulate the host immune response against tumor cells.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,subcellular location:Seems to also be secreted in plasma by cancerous cells but at a low level.,tissue specificity:Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).,
组织表达
Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).
细胞定位
Cytoplasm . Seems to also be secreted in plasma by cancerous cells but at a low level.
功能
developmental stage:Its expression is closely related to cellular differentiation in both normal and malignant squamous cells.,function:May act as a protease inhibitor to modulate the host immune response against tumor cells.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,subcellular location:Seems to also be secreted in plasma by cancerous cells but at a low level.,tissue specificity:Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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