BD-PT5318

IDH3A Rabbit Polyclonal Antibody

IDH3A; Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha

常规抗体

IDH3A

Isocitrate dehydrogenase [NAD] subunit alpha mitochondrial

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

3419

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3419

P50213

http://www.uniprot.org/uniprotkb/P50213/entry

67834

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67834

Q9D6R2

http://www.uniprot.org/uniprot/Q9D6R2

114096

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=114096

Q99NA5

http://www.uniprot.org/uniprot/Q99NA5

Synthesized peptide derived from the Internal region of human IDH3A.

IDH3A Polyclonal Antibody detects endogenous levels of IDH3A protein.

WB 1:500-2000

39kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008],

Brain,Brain cortex,Cajal-Retzius cell,Esophagus tumor,Fetal

Mitochondrion.

Citrate cycle (TCA cycle);

catalytic activity:Isocitrate + NAD(+) = 2-oxoglutarate + CO(2) + NADH.,cofactor:Binds 1 magnesium or manganese ion per subunit.,similarity:Belongs to the isocitrate and isopropylmalate dehydrogenases family.,subunit:Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.