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SYCM Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PN3163
产品名称
SYCM Rabbit Polyclonal Antibody
别名
Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)
类别
常规抗体
基因名称
CARS2 OK/SW-cl.10
蛋白名称
SYCM
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.121% New type preservative N.
Human Gene ID
79587
Human Gene Link
https://www.uniprot.org/uniprot/79587
Human Swissprot No.
Q9HA77
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9HA77/entry
Mouse Gene ID
71941
Mouse Gene Link
https://www.uniprot.org/uniprot/71941
Mouse Swissprot No.
Q8BYM8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BYM8
免疫原
Synthesized peptide derived from human SYCM AA range: 95-145
特异性
This antibody detects endogenous levels of SYCM at Human/Mouse
稀释度
WB 1:500-2000
预测分子量
60kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a putative member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of cysteine to tRNA molecules. A splice-site mutation in this gene has been associated with a novel progressive myoclonic epilepsy disease with similar symptoms to MERRF syndrome. [provided by RefSeq, Mar 2015],
组织表达
Colon adenocarcinoma,Lung,Lymph node,Mammary gland,Salivary gland,Testis,
细胞定位
Mitochondrion matrix .
功能
catalytic activity:ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the class-I aminoacyl-tRNA synthetase family.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

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